More than 96% of participants received both injections, and 2.2% had evidence (serologic, virologic, or both) of SARS-CoV-2 infection at baseline.
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The trial enrolled 30,420 volunteers who were randomly assigned in a 1:1 ratio to receive either vaccine or placebo (15,210 participants in each group).
The primary end point was prevention of Covid-19 illness with onset at least 14 days after the second injection in participants who had not previously been infected with SARS-CoV-2. Persons at high risk for SARS-CoV-2 infection or its complications were randomly assigned in a 1:1 ratio to receive two intramuscular injections of mRNA-1273 (100 μg) or placebo 28 days apart. This phase 3 randomized, observer-blinded, placebo-controlled trial was conducted at 99 centers across the United States. The mRNA-1273 vaccine is a lipid nanoparticle-encapsulated mRNA-based vaccine that encodes the prefusion stabilized full-length spike protein of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes Covid-19. SRO Lounge: Known for its great jukebox, long history in the neighborhood, and a location that's much closer to downtown than the gay bars in Hillcrest, the SRO has a strong following among drag queens and their fans, but all kinds tend to drop by here, albeit not necessarily in large numbers.Vaccines are needed to prevent coronavirus disease 2019 (Covid-19) and to protect persons who are at high risk for complications.Leather, uniforms, military gear, and the like are the preferred attire. Eagle Bar: As bars with the name Eagle go, the Eagle is your classic dude's leather club, a place where real men cruise for real men.Park & Rec: Set in the space formerly occupied by the popular gay bar Bourbon Street, this is an expansive nightspot and restaurant that still draws plenty of LGBT folks and open-minded revelers.Pecs: Regulars tend to be of the local, bearish crowd and this bar is well-known for hosting a wonderfully long happy hour and a convivial staff.Number One Fifth Avenue: A great all-around neighborhood gay bar, it balances an intimate ambiance and friendly atmosphere without the tired, divey feel that sometimes dominates in smaller lounges.There's a good beer and wine selection, but martinis are, of course, the libation of choice.
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The space is attractive, nicely lit, and comfortable, with a full menu of upscale, contemporary American fare.
The Hole in the Wall: Famously popular with Navy and other military personnel, it's right in the heart of Point Loma and is renowned for its huge, atmospheric patio and legendary Sunday afternoon parties.Cheers: A cozy, slightly off-the-beaten-path neighborhood spot in charming University Heights, Cheers is exactly what its name suggests: a laid-back spot where everybody knows your name, or, at the very least, even outsiders will be treated as friends.